Changes in plasma PLAC-1 concentration and its expression during early-mid pregnancy in bovine placental tissues – a pilot study

Autor:	Monika Jamioł, Magdalena Sozoniuk, Jacek Wawrzykowski, Marta Kankofer
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	Bovine pregnancy Placenta-specific protein 1 PLAC1 Bovine placenta Veterinary medicine SF600-1100
Zdroj:	BMC Veterinary Research, Vol 20, Iss 1, Pp 1-9 (2024)
Druh dokumentu:	article
ISSN:	1746-6148
DOI:	10.1186/s12917-024-03898-z
Popis:	Abstract Background Placenta-specific protein 1 (PLAC1) is a small secreted protein considered to be a molecule with a significant role in the development of the placenta and the establishment of the mother-foetus interface. This study aimed to confirm the presence of bovine PLAC1 and to examine its profile in the placenta and plasma in the first six months of pregnancy. The expression pattern of PLAC1 was analysed by RT-qPCR and Western Blotting. Quantitative evaluation was carried out using ELISA. Results PLAC1 concentrations in the plasma of pregnant cows were significantly higher (p
Databáze:	Directory of Open Access Journals
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