Revolutionizing deceased donor transplantation: How new approaches to machine perfusion broadens the horizon for organ donation

Autor: Stephanie Almeida, William Snyder, Mita Shah, Jonathan Fisher, Christopher Marsh, Alana Hawkes, Diana Gorial, Sean DeWolf, Dianne B. McKay
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Transplantation Reports, Vol 9, Iss 3, Pp 100160- (2024)
Druh dokumentu: article
ISSN: 2451-9596
DOI: 10.1016/j.tpr.2024.100160
Popis: Solid organ transplantation is lifesaving for persons with end-stage organ disease. Thanks to advancements in organ preservation, surgeons are now able to successfully transplant organs that were previously considered high risk for poor graft function. Innovations in perfusion machine types, preservation solutions and additives to preservation solutions have significantly improved the ability to utilize organs previously thought unusable.Newer organ preservation techniques are offering a promising outlook for extending graft longevity and improving transplant outcomes. This review explores the impact of deceased donor type on graft quality and highlights emerging strategies designed to improve the function and viability of deceased donor organs.
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