In Vivo Antigen Expression Regulates CD4 T Cell Differentiation and Vaccine Efficacy against Mycobacterium tuberculosis Infection

Autor: Helena Strand Clemmensen, Jean-Yves Dube, Fiona McIntosh, Ida Rosenkrands, Gregers Jungersen, Claus Aagaard, Peter Andersen, Marcel A. Behr, Rasmus Mortensen
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: mBio, Vol 12, Iss 2 (2021)
Druh dokumentu: article
ISSN: 2150-7511
DOI: 10.1128/mBio.00226-21
Popis: Tuberculosis, caused by Mtb, constitutes a global health crisis of massive proportions, and the impact of the current coronavirus disease 2019 (COVID-19) pandemic is expected to cause a rise in tuberculosis-related deaths. Improved vaccines are therefore needed more than ever, but a lack of knowledge on protective immunity hampers their development.
Databáze: Directory of Open Access Journals