Effect of tramadol gargle on postoperative sore throat: A double blinded randomized placebo controlled study

Autor: Samaa Rashwan, Ashraf Abdelmawgoud, Ahmed A. Badawy
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Egyptian Journal of Anaesthesia, Vol 30, Iss 3, Pp 235-239 (2014)
Druh dokumentu: article
ISSN: 1110-1849
DOI: 10.1016/j.egja.2014.01.010
Popis: Background: Postoperative sore throat is an undesirable complaint after general anesthesia with laryngeal mask airway. Tramadol is a synthetic codeine analogue with NMDA receptor antagonist and local anesthetic effects. We compared tramadol gargle to placebo given 5 min before surgery on attenuating postoperative sore throat for 24 postoperative hours. Method: In a prospective randomized double blind study, fifty patients of ASA I and II, undergoing elective moderate urological surgery under general anesthesia using laryngeal mask airway were allocated into two groups (25 patients each); all patients were asked to gargle for 1 min with 30 ml apple juice containing tramadol 2 mg/kg in group (T), and nothing in group (P) 5 min before surgery. The incidence and the severity of postoperative sore throat were graded at 2, 6, 12, and 24 h after surgery using a four-point scale. Result: Incidence and severity of postoperative sore throat were significantly less in tramadol treated group compared to placebo group at 2, 6, 12, and 24 h (p
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