| Autor: |
Ibrahim Kargbo-Labour, Victoria Redwood-Sawyerr, Abdulai Conteh, Elisabeth Chop, Mohamed S. Bah, Abdulai Koroma, Unidiatu Kabia, Luke Klein, Sugandh Juneja, Patricia Houck, Steven Reid, Darin Evans, Angela M. Weaver, Anna E. Phillips, Yaobi Zhang |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Frontiers in Public Health, Vol 12 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2296-2565 |
| DOI: |
10.3389/fpubh.2024.1415486 |
| Popis: |
BackgroundBaseline mapping showed that schistosomiasis was highly/moderately endemic in nine districts in Sierra Leone. Mass drug administration (MDA) with praziquantel started in 2009, and after multiple rounds of treatment, an impact assessment was conducted in 2016 followed by a second re-assessment in 2022 using cluster sampling to provide more granular data for refining chiefdom (sub-district) treatment strategies.MethodsOn average, 20 rural villages were systematically selected per district by probability proportional to population size across the nine districts. Surveys were conducted in schools, and 24 school children aged between 5 and 14 years were randomly selected, with an equal number of boys and girls. One stool sample and one urine sample were collected per child. Two Kato-Katz slides were examined per stool for Schistosoma mansoni infection. Hemastix strips were used as a proxy for S. haematobium infection with urine filtration used for egg counts on hematuria-positive samples.ResultsIn total, 4,736 stool samples and 4,618 urine samples were examined across 200 schools in 125 chiefdoms. Overall, the prevalence of S. mansoni was 16.3% (95% CI: 15.3–17.4%), while the overall prevalence of S. haematobium was 2.0% (95% CI: 1.6–2.4%) by hematuria. The prevalence of heavy infections for S. mansoni and S. haematobium was 1.5% (95% CI: 1.1–1.9%) and 0.02% (95% CI: 0.0–0.14%), respectively. Among 125 chiefdoms surveyed, the overall schistosomiasis prevalence was |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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