Chemical leukoderma induced by dimethyl sulfate

Autor: Maya Valeska Gozali, Jia-an Zhang, Fei Yi, Bing-rong Zhou, Dan Luo
Jazyk: English<br />Portuguese
Rok vydání: 2016
Předmět:
Zdroj: Anais Brasileiros de Dermatologia, Vol 91, Iss 5 suppl 1, Pp 26-28 (2016)
Druh dokumentu: article
ISSN: 0365-0596
1806-4841
DOI: 10.1590/abd1806-4841.20164972
Popis: Abstract Chemical leukoderma occurs due to the toxic effect of a variety of chemical agents. Mechanisms include either destruction or inhibition of melanocytes. We report two male patients (36 and 51 years old) who presented with multiple hypopigmented macules and patches on the neck, wrist, and legs after exposure to dimethyl sulfate in a chemical industry. Physical examination revealed irregular depigmentation macules with sharp edges and clear hyperpigmentation around the lesions. History of repeated exposure to a chemical agent can help the clinical diagnosis of chemical leukoderma. This diagnosis is very important for prognosis and therapeutic management of the disease.
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