Papillary renal cell carcinoma with lipocyte-like cells: A rare morphological variant or an indication of aggressiveness?

Autor: Sari Aysegul, Evcim Gozde, Ermete Murat, Bal Kaan, Bolukbasi Ahmet
Jazyk: angličtina
Rok vydání: 2010
Předmět:
Zdroj: Indian Journal of Pathology and Microbiology, Vol 53, Iss 3, Pp 541-543 (2010)
Druh dokumentu: article
ISSN: 0377-4929
0974-5130
Popis: Papillary renal cell carcinoma (PRCC) is the second most common carcinoma of the kidney, which is classified into two types. Type 1 displays single layer of cells with scanty pale cytoplasm and type 2 has pseudostratified high-grade nuclei with eosinophilic cytoplasm. Recently, apart from these two types, oncocytic PRCC and clear-cell PRCC have been described. To the best of our knowledge, lipocyte-like cells have not yet been reported to accompany any subtypes of renal cell carcinoma. Herein, we report a case of PRCC with lipocyte-like cells and sarcomatoid features. Lipocyte-like cells might represent a special type of PRCC or this feature may be an indication of poor prognosis regarding its association with sarcomatoid change.
Databáze: Directory of Open Access Journals