| Autor: |
Kaitao Li, Zhou Yuan, Jintian Lyu, Eunseon Ahn, Simon J. Davis, Rafi Ahmed, Cheng Zhu |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-021-22965-9 |
| Popis: |
The mechanistic detail of how PD-1 inhibits T cell activation is lacking. Here, the authors show PD-1 suppresses the cooperative TCR–pMHC–CD8 interaction by inhibiting TCR proximal signalling. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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Full text from SpringerLink