Imaging Constructs: The Rise of Iron Oxide Nanoparticles

Autor: Bianca Elena-Beatrice Crețu, Gianina Dodi, Amin Shavandi, Ioannis Gardikiotis, Ionela Lăcrămioara Șerban, Vera Balan
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Molecules, Vol 26, Iss 11, p 3437 (2021)
Druh dokumentu: article
ISSN: 1420-3049
DOI: 10.3390/molecules26113437
Popis: Over the last decade, an important challenge in nanomedicine imaging has been the work to design multifunctional agents that can be detected by single and/or multimodal techniques. Among the broad spectrum of nanoscale materials being investigated for imaging use, iron oxide nanoparticles have gained significant attention due to their intrinsic magnetic properties, low toxicity, large magnetic moments, superparamagnetic behaviour and large surface area—the latter being a particular advantage in its conjunction with specific moieties, dye molecules, and imaging probes. Tracers-based nanoparticles are promising candidates, since they combine synergistic advantages for non-invasive, highly sensitive, high-resolution, and quantitative imaging on different modalities. This study represents an overview of current advancements in magnetic materials with clinical potential that will hopefully provide an effective system for diagnosis in the near future. Further exploration is still needed to reveal their potential as promising candidates from simple functionalization of metal oxide nanomaterials up to medical imaging.
Databáze: Directory of Open Access Journals
Nepřihlášeným uživatelům se plný text nezobrazuje