Ruthenium(II)-enabled para-selective C–H difluoromethylation of anilides and their derivatives

Autor: Chunchen Yuan, Lei Zhu, Changpeng Chen, Xiaolan Chen, Yong Yang, Yu Lan, Yingsheng Zhao
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-018-03341-6
Popis: Selective para-functionalization of substituted arenes is a formidable challenge in homogeneous catalysis. Here, the authors achieved the para-selective C-H difluoromethylation of anilides, indolines and tetrahydroquinolines with a ruthenium catalyst in good yields and apply it to the synthesis of bioactive compounds.
Databáze: Directory of Open Access Journals