Effects of Labisia pumila on oxidative stress in rat model of post-menopausal osteoporosis

Autor: Nurdiana Nurdiana, Nelly Mariati, Noorhamdani Noorhamdani, Bambang Setiawan, Nicolaas Budhiparama, Zairin Noor
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Asian Pacific Journal of Reproduction, Vol 5, Iss 5, Pp 391-394 (2016)
Druh dokumentu: article
ISSN: 2305-0500
DOI: 10.1016/j.apjr.2016.07.015
Popis: Objective: To analyze the effects of Labisia pumila (L. pumila) extract on the markers of oxidative stress in ovariectomized rats. Methods: Twenty-five female Wistar rats were divided into five treatment groups (n = 5): the control group, the ovariectomized group, the ovariectomized group treated with L. pumila extract of various doses (10 mg/kg, 20 mg/kg, and 40 mg/kg). L. pumila extract was administered daily for 8 weeks. Results: The levels of malondialdehyde and superoxide dismutase (SOD) were subjected to spectrophotometric analysis. Serum levels of malondialdehyde and SOD were significantly higher in the group of rat model of post-menopausal osteoporosis than that of the control group (P
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