STN DBS for Advanced Parkinson Disease Simultaneously Alleviates Cluster Headache

Autor: Antti Huotarinen, Martin Reich, Jens Volkmann, Eero Pekkonen
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Case Reports in Neurology, Vol 9, Iss 3, Pp 289-292 (2017)
Druh dokumentu: article
ISSN: 1662-680X
DOI: 10.1159/000481850
Popis: Background: STB DBS (deep brain stimulation of the subthalamic nucleus) is commonly used to treat advanced Parkinson disease (PD) while posterior hypothalamic DBS for cluster headache (CH) remains experimental. Methods: We present a case where a middle-aged man was diagnosed with both CH and PD and received medical treatment for both. The patient was treated with bilateral STN DBS after developing side effects related to L-dopa. Findings: STN DBS not only alleviated PD symptoms but also the CH, and hence the CH treatment could be withdrawn. During follow-up PD progressed but the effect on CH symptoms was sustained. Conclusions: The anatomical proximity of the medial STN and hypothalamus, their similar connectivity via the hyperdirect pathway, and the autonomic effects of STN DBS could explain symptom relief for both PD and CH.
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