Potential Applicability of Perioperative Thromboelastography to Access the Coagulopathies in Live-Related Renal Transplantation – A Prospective Observational Pilot Study

Autor: Amal Francis Sam, Sandeep Sahu, Karthik T Ponnappan, Zakia Saeed, Gaurav Sindwani, Aneesh Srivastava, Narayan Prasad
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Saudi Journal of Kidney Diseases and Transplantation, Vol 32, Iss 4, Pp 1043-1053 (2021)
Druh dokumentu: article
ISSN: 1319-2442
DOI: 10.4103/1319-2442.338278
Popis: Ischemic and reperfusion injury (IRI) occurs during organ transplantation. IRI during liver transplantation is well studied and established; results in coagulopathy due to release of heparin-like substances and platelet trapping. During renal transplantation, similar IRI phenomenon occurs, and thromboelastography (TEG) can be used to detect and manage coagulopathy. The preoperative, immediate postreperfusion, and postoperative day 1 TEG was done on 25 cases of live-related renal transplantation. Coagulopathy was defined by deranged and abnormal TEG variables values from baseline and supported by the clinical presence of nonsurgical oozing and bleeding in the surgical field. The postreperfusion TEG values showed coagulopathic changes. About 64% of patients had R-time (RT) more than 12 min, 64% of patients showed maximum amplitude (MA)
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