| Autor: |
Marlon Yovera-Aldana, Victor Velásquez-Rimachi, Andrely Huerta-Rosario, M D More-Yupanqui, Mariela Osores-Flores, Ricardo Espinoza, Fradis Gil-Olivares, César Quispe-Nolazco, Flor Quea-Vélez, Christian Morán-Mariños, Isabel Pinedo-Torres, Carlos Alva-Diaz, Kevin Pacheco-Barrios |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
PLoS ONE, Vol 16, Iss 5, p e0251642 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
1932-6203 |
| DOI: |
10.1371/journal.pone.0251642 |
| Popis: |
AimsThe objective of this systematic review and meta-analysis is to estimate the prevalence and incidence of diabetic peripheral neuropathy (DPN) in Latin America and the Caribbean (LAC).Materials and methodsWe searched MEDLINE, SCOPUS, Web of Science, EMBASE and LILACS databases of published observational studies in LAC up to December 2020. Meta-analyses of proportions were performed using random-effects models using Stata Program 15.1. Heterogeneity was evaluated through sensitivity, subgroup, and meta-regression analyses. Evidence certainty was performed with the GRADE approach.ResultsTwenty-nine studies from eight countries were included. The estimated prevalence of DPN was 46.5% (95%CI: 38.0-55.0) with a significant heterogeneity (I2 = 98.2%; pConclusionThe overall prevalence of DPN is high in LAC with significant heterogeneity between and within countries that could be explained by population type and methodological aspects. Significant gaps (e.g., under-representation of most countries, lack of incidence studies, and heterogenous case definition) were identified. Standardized and population-based studies of DPN in LAC are needed. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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