Prevalence of Trypanosoma cruzi/HIV coinfection in southern Brazil

Autor: Dulce Stauffert, Mariangela Freitas da Silveira, Marília Arndt Mesenburg, Adriane Brod Manta, Alessandra da Silva Dutra, Guilherme Lucas de Oliveira Bicca, Marcos Marreiro Villela
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Brazilian Journal of Infectious Diseases, Vol 21, Iss 2, Pp 180-184 (2017)
Druh dokumentu: article
ISSN: 1413-8670
DOI: 10.1016/j.bjid.2016.10.006
Popis: Chagas disease reactivation has been a defining condition for acquired immune deficiency syndrome in Brazil for individuals coinfected with Trypanosoma cruzi and HIV since 2004. Although the first coinfection case was reported in the 1980s, its prevalence has not been firmly established. In order to know coinfection prevalence, a cross-sectional study of 200 HIV patients was performed between January and July 2013 in the city of Pelotas, in southern Rio Grande do Sul, an endemic area for Chagas disease. Ten subjects were found positive for T. cruzi infection by chemiluminescence microparticle immunoassay and indirect immunofluorescence. The survey showed 5% coinfection prevalence among HIV patients (95% CI: 2.0–8.0), which was 3.8 times as high as that estimated by the Ministry of Health of Brazil. Six individuals had a viral load higher than 100,000 copies per μL, a statistically significant difference for T. cruzi presence. These findings highlight the importance of screening HIV patients from Chagas disease endemic areas. Keywords: Chagas disease, Trypanosoma cruzi, AIDS
Databáze: Directory of Open Access Journals