Relationship between endothelial function and skeletal muscle strength in community dwelling elderly women

Autor: Jun‐Il Yoo, Mi‐Ji Kim, Jae‐Bum Na, Yun‐Hong Chun, Young‐Jin Park, Yongwhi Park, Young‐Sool Hah, Yong‐Chan Ha, Ki Soo Park
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Journal of Cachexia, Sarcopenia and Muscle, Vol 9, Iss 6, Pp 1034-1041 (2018)
Druh dokumentu: article
ISSN: 2190-6009
2190-5991
DOI: 10.1002/jcsm.12340
Popis: Abstract Background The aim of this study is to determine whether there is correlation between endothelial function and skeletal muscle function measured by hand grip strength in elderly women. Methods This cross‐sectional study used data of NAMGARAM‐2 cohort. The NAMGARAM‐2 cohort consisted of a group of people living in three rural communities. They were enrolled for studies on activity limitation due to age‐related musculoskeletal disorders including knee osteoarthritis, osteoporosis, and sarcopenia. They were residents aged 40 years or older. They agreed to participate in this cohort from March 2016 to May 2017. Peripheral endothelial function was assessed by reactive hyperaemia‐peripheral arterial tonometry using EndoPAT2000 system. Hand grip strength was measured using a digital hand dynamometer. Results Endothelial function index assessed by EndoPAT was worse in the low grip strength group than that in the normal group of elderly women (1.54 ± 0.51 in the low grip strength group vs. 1.77 ± 0.67 in the normal group, P = 0.003). There was a positive correlation between hand grip strength and endothelial function (r = 0.176, P = 0.007). On stepwise multivariate analysis, endothelial dysfunction (reactive hyperaemia‐peripheral arterial tonometry index
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