Expanding laparoscopic pancreaticoduodenectomy to pancreatic-head and periampullary malignancy: major findings based on systematic review and meta-analysis

Autor: Ke Chen, Xiao-long Liu, Yu Pan, Hendi Maher, Xian-fa Wang
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: BMC Gastroenterology, Vol 18, Iss 1, Pp 1-12 (2018)
Druh dokumentu: article
ISSN: 1471-230X
DOI: 10.1186/s12876-018-0830-y
Popis: Abstract Background Laparoscopic pancreaticoduodenectomy (LPD) remains to be established as a safe and effective alternative to open pancreaticoduodenectomy (OPD) for pancreatic-head and periampullary malignancy. The purpose of this meta-analysis was to compare LPD with OPD for these malignancies regarding short-term surgical and long-term survival outcomes. Methods A literature search was conducted before March 2018 to identify comparative studies in regard to outcomes of both LPD and OPD for the treatment of pancreatic-head and periampullary malignancies. Morbidity, postoperative pancreatic fistula (POPF), mortality, operative time, estimated blood loss, hospitalization, retrieved lymph nodes, and survival outcomes were compared. Results Among eleven identified studies, 1196 underwent LPD, and 8247 were operated through OPD. The pooled data showed that LPD was associated with less morbidity (OR = 0.57, 95%CI: 0.41~ 0.78, P
Databáze: Directory of Open Access Journals
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