Assessing heart rate variability in type 1 diabetes mellitus—Psychosocial stress a possible confounder

Autor: Eva Kristiansen, Pär Wanby, Karin Åkesson, Peter Blomstrand, Lars Brudin, Johanna Thegerström
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Annals of Noninvasive Electrocardiology, Vol 25, Iss 5, Pp n/a-n/a (2020)
Druh dokumentu: article
ISSN: 1542-474X
1082-720X
DOI: 10.1111/anec.12760
Popis: Abstract Background Autonomic neuropathy (AN) commonly arises as a long‐term complication in diabetes mellitus and can be diagnosed from heart rate variability (HRV), calculated from electrocardiogram recordings. Psychosocial stress also affects HRV and could be one of several confounders for cardiac AN. The present work investigated the impact of psychosocial stress on HRV in individuals with type 1 diabetes mellitus (T1DM) and assessed the use of salivary cortisol as a biomarker for psychosocial stress in this context. Methods A total of 167 individuals 6–60 years old (113 with T1DM and 54 healthy controls) underwent 24‐hr ECG recordings with HRV analysis. Salivary cortisol was sampled thrice during the registration day. Perceived psychosocial stress along with other factors of possible importance for the interpretation of HRV was documented in a diary. Results Heart rate variability (high‐frequency power during sleep) was reduced (p
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