Patients with progression of spinal metastases who present to the clinic have better outcomes compared to those who present to the emergency department

Autor: Joseph R. Linzey, Varun G. Kathawate, Michael J. Strong, Kayla Roche, Peyton E. Goethe, Lila R. Tudrick, Johan Lee, Arushi Tripathy, Sravanthi Koduri, Ayobami L. Ward, Oludotun Ogunsola, Mark M. Zaki, Rushikesh S. Joshi, Grant Weyburne, Charles S. Mayo, Joseph R. Evans, William C. Jackson, Nicholas J. Szerlip
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Cancer Medicine, Vol 12, Iss 19, Pp 20177-20187 (2023)
Druh dokumentu: article
ISSN: 2045-7634
DOI: 10.1002/cam4.6601
Popis: Abstract Background As cancer therapies have improved, spinal metastases are increasingly common. Resulting complications have a significant impact on patient's quality of life. Optimal methods of surveillance and avoidance of neurologic deficits are understudied. This study compares the clinical course of patients who initially presented to the emergency department (ED) versus a multidisciplinary spine oncology clinic and who underwent stereotactic body radiation therapy (SBRT) secondary to progression/presentation of metastatic spine disease. Methods We performed a retrospective analysis of a prospectively maintained database of adult oncologic patients who underwent spinal SBRT at a single hospital from 2010 to 2021. Descriptive statistics and survival analyses were performed. Results We identified 498 spinal radiographic treatment sites in 390 patients. Of these patients, 118 (30.3%) presented to the ED. Patients presenting to the ED compared to the clinic had significantly more severe spinal compression (52.5% vs. 11.7%; p
Databáze: Directory of Open Access Journals
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