Coffee and Green Tea Consumption With the Risk of COVID-19 Among the Vaccine Recipients in Japan: A Prospective Study

Autor: Zobida Islam, Shohei Yamamoto, Tetsuya Mizoue, Maki Konishi, Norio Ohmagari
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of Epidemiology, Vol 34, Iss 9, Pp 444-452 (2024)
Druh dokumentu: article
ISSN: 0917-5040
1349-9092
DOI: 10.2188/jea.JE20230231
Popis: Background: While coffee and green tea have been suggested to have immunoprotective effects, it remains elusive whether they can decrease the risk of coronavirus disease 2019 (COVID-19). Objective: We prospectively examined the associations of coffee and green tea consumption with the risk of COVID-19 among mRNA vaccine recipients during the epidemic of the Omicron variant. Methods: Participants were 2,110 staff (aged 18 to 76 years) of a large medical facility in Tokyo, who attended a serosurvey in June 2022, predominantly received ≥3 doses of vaccine, and were followed for COVID-19 until December 2022. Coffee and green tea consumption was ascertained via a questionnaire. COVID-19 was identified through the in-house registry. Cox proportional hazards model was used to estimate the hazard ratios (HRs) of COVID-19 across the categories of beverage consumption. Results: During 6 months of follow-up, 225 (10.6%) cases of COVID-19 were identified. Contrary to the expectation, higher consumption of coffee was associated with a significant increase in the risk of COVID-19; multivariable-adjusted HRs were 1.00 (reference), 0.92 (95% confidence interval [CI], 0.62–1.35), 1.48 (95% CI, 0.99–2.22), and 1.82 (95% CI, 1.20–2.76) for
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