Prognostic Models of Primary Sclerosing Cholangitis
| Autor: | A. I. Dolgushina, A. A. Selyanina, V. V. Dubrovina, G. A. Isyangildina, E. R. Olevskaya |
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| Jazyk: | ruština |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Российский журнал гастроэнтерологии, гепатологии, колопроктологии, Vol 32, Iss 5, Pp 43-50 (2023) |
| Druh dokumentu: | article |
| ISSN: | 1382-4376 2658-6673 |
| DOI: | 10.22416/1382-4376-2022-32-5-43-50 |
| Popis: | Aim: to study the significance of prognostic scales in a target group of patients with primary sclerosing cholangitis (PSC) living in the Chelyabinsk region.Materials and methods. The study included 21 patients with a confirmed diagnosis of primary sclerosing cholangitis (PSC) and a disease duration of at least two years. The primary endpoint studied was death. The MELD, Mayo Risk Score, Amsterdam-Oxford PSC Score, PREsTo score, and UK-PSC Score scales were calculated based on the medical records. Statistical processing was carried out using the SPSS Statistics v.22 application.Results. A retrospective assessment of the risk of mortality using the MELD, Mayo Risk Score and Amsterdam-Oxford PSC Score did not reveal a statistically significant difference between deceased and surviving patients. The UK-PSC Score scale showed the highest predictive value (p = 0.046).Conclusion. The new predictive model UK-PSC Score showed advantages in predicting death in PSC patients compared to other scales. |
| Databáze: | Directory of Open Access Journals |
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