Disposable Microfluidic Sensor Based on Nanocellulose for Glucose Detection

Autor: Khan Mohammad Ahsan Uddin, Ville Jokinen, Farzin Jahangiri, Sami Franssila, Orlando J. Rojas, Sampo Tuukkanen
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Global Challenges, Vol 3, Iss 2, Pp n/a-n/a (2019)
Druh dokumentu: article
ISSN: 2056-6646
DOI: 10.1002/gch2.201800079
Popis: Abstract Point‐of‐care devices that are inexpensive, disposable, and environmentally friendly are becoming increasingly predominant in the field of biosensing and biodiagnostics. Here, microfluidics is a suitable option to endow portability and minimal reagent and material consumption. Nanocellulose is introduced to manufacture microfluidic channels and as a storage and immobilization compartment of glucose oxidase. Improved enzymatic activity retention is demonstrated in a simple and disposable point‐of‐care diagnostic unit that is able to detect glucose from fluid matrices at 0.1 × 10−3m concentration and in less than 10 min. It is concluded that the patterning and fluidic technologies that are possible with nanocellulose enable easily scalable multianalyte designs.
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