The immune microenvironment of lung adenocarcinoma featured with ground‐glass nodules

Autor:	Changtai Zhao, Rongxin Xiao, Hongming Jin, Xiao Li
Jazyk:	angličtina
Rok vydání:	2024
Předmět:	B cell ground‐glass nodules T cell tumor immune microenvironment lung adenocarcinoma Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Zdroj:	Thoracic Cancer, Vol 15, Iss 19, Pp 1459-1470 (2024)
Druh dokumentu:	article
ISSN:	1759-7714 1759-7706
DOI:	10.1111/1759-7714.15380
Popis:	Abstract Early‐stage lung cancer is now more commonly identified in the form of ground‐glass nodules (GGNs). Presently, the treatment of lung cancer with GGNs mainly depends on surgery; however, issues still exist such as overtreatment and delayed treatment due to the nonuniform standard of follow‐up. Therefore, the discovery of a noninvasive treatment could expand the treatment repertoire of ground‐glass nodular lung cancer and benefit the prognosis of patients. Immunotherapy has recently emerged as a new promising approach in the field of lung cancer treatment. Thus, this study presents a comprehensive review of the immune microenvironment of lung cancer with GGNs and describes the functions and characteristics of various immune cells involved, aiming to provide guidance for the clinical identification of novel immunotherapeutic targets.
Databáze:	Directory of Open Access Journals
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