Biochemical and physiological characteristics of neonates born to mothers with diabetes during gestation

Autor: Milašinović Ljubomir, Hrabovski Ivan, Grujić Zorica, Bogavac Mirjana, Nikolić Aleksandra
Jazyk: angličtina
Rok vydání: 2012
Předmět:
Zdroj: Journal of Medical Biochemistry, Vol 31, Iss 1, Pp 47-52 (2012)
Druh dokumentu: article
ISSN: 1452-8258
1452-8266
Popis: The aim of this study was to investigate how glucose homeostasis disorders influence biochemical homeostasis and fetal maturation. A prospective randomized study included 102 infants: 31 newborns of mothers with glucose homeostasis disorders (Group I) and 71 newborns of healthy mothers (Group II). In the pregnant women, the mean age, body weight and height, BMI, parity, duration of the disease and the mode of labor were estimated. The following procedures were performed in each new born infant: physical examination, de termination of Apgar score, measurements of birth weight and length, estimation of neurological status, clinical estimation of gestational age, ECG and ultrasonography of the brain, as well as the basic hematologic, biochemical and microbiological analyses. Newborn infants of diabetic pregnancies were small for gestational age and of high birth weight. The levels of Na+, K+ and Cl- ions did not show significant differences between the investigated groups, where as the levels of total Ca and Mg were significantly decreased (2.18±0.59 and 0.65±0.17 mmol/L) (p
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