| Autor: |
Francesco Bertoni, Sergio B. Cogliatti, Daniela Capello, Xi-shan Hao, Hua-qing Wang, Hui-lai Zhang, Franco Cavalli |
| Jazyk: |
angličtina |
| Rok vydání: |
2011 |
| Předmět: |
|
| Zdroj: |
Cancer Biology & Medicine, Vol 8, Iss 2, Pp 65-70 (2011) |
| Druh dokumentu: |
article |
| ISSN: |
2095-3941 |
| DOI: |
10.1007/s11805-011-0561-0 |
| Popis: |
Mantle cell lymphoma (MCL) is an aggressive non-Hodgkin’s lymphoma, originating from naı ¨ve B-cells. The blastoid MCL tumors often show complex cytogenetic aberrations. In this review, we summarized the data available on immunoglobulin heavy-chain (IgH) genes rearrangement for their importance in suggesting the MCL normal counterpart B-cell. Some new data suggesting an antigen selection process were also presented in this review. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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