Pleural aspergillosis in a patient with recurrent spontaneous pneumothorax: The challenge of an optimal therapeutic approach

Autor: Isabel Abreu, Mariana Guedes, Raquel Duro, Sara Lopes, João Maciel, Lurdes Santos
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Medical Mycology Case Reports, Vol 28, Iss , Pp 4-7 (2020)
Druh dokumentu: article
ISSN: 2211-7539
DOI: 10.1016/j.mmcr.2020.02.004
Popis: Pleural aspergillosis (PA) is a rare but potentially fatal disease. Most cases are secondary to bronchopleural fistulae or pleural intervention and can occur in the absence of immunosuppression.We report a case of PA in a young patient after pleurodesis for recurrent pneumothorax. Clinical resolution was achieved with systemic and local antifungal therapy combined with surgical debridement. Hepatotoxicity led to a switch from voriconazole to isavuconazole, with a successful outcome.
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