| Autor: |
Tsuey-Pin Lin, Ya-Fang Chiu, Li-Kwan Chang, Ching-Yi Yiu, Shih-Ying Chen |
| Jazyk: |
angličtina |
| Rok vydání: |
2010 |
| Předmět: |
|
| Zdroj: |
Molecules, Vol 15, Iss 10, Pp 7115-7124 (2010) |
| Druh dokumentu: |
article |
| ISSN: |
1420-3049 |
| DOI: |
10.3390/molecules15107115 |
| Popis: |
Reactivation of Epstein-Barr virus (EBV) from latency to the lytic cycle is required for the production of viral particles. Here, we examine the capacity of resveratrol to inhibit the EBV lytic cycle. Our results show that resveratrol inhibits the transcription of EBV immediate early genes, the expression of EBV lytic proteins, including Rta, Zta, and EA-D and reduces viron production, suggesting that this compound may be useful for preventing the proliferation of the virus. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
