| Autor: |
Piet Geusens, Jacqueline R Center, Tuan V Nguyen, Thach Tran, Johanna Driessen, Joop P van den Bergh, John Eisman, Caroline E Wyers, Lisanne Vranken, Robert Y Van der Velde, Heinrich M J Janzing, Sjoerd Kaarsemakers, Dana Bliuc |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
BMJ Open, Vol 12, Iss 7 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2044-6055 |
| DOI: |
10.1136/bmjopen-2021-058983 |
| Popis: |
Objectives To evaluate the risk of subsequent fractures in patients who attended the Fracture Liaison Service (FLS), with and without incident falls after the index fracture.Design A 3-year prospective observational cohort study.Setting An outpatient FLS in the Netherlands.Participants Patients aged 50+ years with a recent clinical fracture.Outcome measures Incident falls and subsequent fractures.Results The study included 488 patients (71.9% women, mean age: 64.6±8.6 years). During the 3-year follow-up, 959 falls had been ascertained in 296 patients (60.7%) (ie, fallers), and 60 subsequent fractures were ascertained in 53 patients (10.9%). Of the fractures, 47 (78.3%) were fall related, of which 25 (53.2%) were sustained at the first fall incident at a median of 34 weeks. An incident fall was associated with an approximately 9-fold (HR: 8.6, 95% CI 3.1 to 23.8) increase in the risk of subsequent fractures.Conclusion These data suggest that subsequent fractures among patients on treatment prescribed in an FLS setting are common, and that an incident fall is a strong predictor of subsequent fracture risk. Immediate attention for fall risk could be beneficial in an FLS model of care.Trial registration number NL45707.072.13. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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