Association of vitamin D levels with severity and outcome of COVID-19 infection among inward patients at a tertiary care unit in Sri Lanka

Autor: P. Mayurathan, G. R. Francis, V. R. Francis, S. I. Majitha, R. Sanjeev, S. Vivekanandan, S. Santharooban, W. M. U. Nishantha, M. M. N. Peries, A. S. M. Safran, S. Shiyananth
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Asian Journal of Internal Medicine, Vol 2, Iss 2 (2023)
Druh dokumentu: article
ISSN: 2827-7260
DOI: 10.4038/ajim.v2i2.84
Popis: Introduction: A link between vitamin D and COVID-19 infection has been expressed by many experts. In this study, we aim to investigate the association of the prevalence of vitamin D deficiency with the severity and outcome of COVID-19 infection in patients who are admitted to Teaching Hospital Batticaloa, Sri Lanka. Methods: A retrospective cross-sectional study was conducted among COVID-19 patients over a period of one month in May 2021. All patients who tested positive for COVID-19 were included. Patients with chronic kidney disease, known vitamin D deficiency, and patients on vitamin D supplements were excluded from the study. The vitamin D deficiency was defined according to the Oxford Academic Endocrine Society guidelines. The severity of the COVID-19 was defined according to the Provisional Clinical Practice Guidelines on COVID-19 suspected and confirmed patients. Primary endpoints of this study were 'recovered from COVID-19' or 'death'. Data was analysed to report the proportion of patients with different vitamin D levels and disease severity. Chi-squared and Fisher's exact tests were used to analyse the results. A p-value of
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