CYTOKINE REGULATION OF ULCEROGENESIS IN GASTRODUODENAL MUCOSA

Autor: L. V. Matveeva, M. A. Stenina, L. M. Mosina
Jazyk: ruština
Rok vydání: 2014
Předmět:
Zdroj: Медицинская иммунология, Vol 15, Iss 2, Pp 107-118 (2014)
Druh dokumentu: article
ISSN: 1563-0625
2313-741X
DOI: 10.15789/1563-0625-2013-2-107-118
Popis: Ulcerogenesis in gastroduodenal mucosa area is a complex multistep process. Its, phases arecontrolled by interaction and activation of pro­ and antiinflammatory cytokine cascade. Present review article summarizes scientific data on impact of cytokines upon ulcerative and reparatory processes, a variety of their diagnostic and therapeutic options is defined. Evaluation of cytokine status, or, in some cases, cytokine genotyping in patients with stomach and duodenal ulcers, may predict clinical course of the disease, as well as efficiency of basic and eradication therapy, correction of the treatment.
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