| Autor: |
Vikash Jaiswal, Song Peng Ang, Muhammad Hanif, Mayank Jha, Vikash Kumar, Abdelmonem Siddiq, Bhavyakumar Vachhani, Anupam Halder, Michelle Koifman, Herby Jeanty, Siddharath Soni, Madeeha Subhan Waleed, Tushar Kumar, Helen Huang, Dhrubajyoti Bandyopadhyay |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
International Journal of Cardiology: Heart & Vasculature, Vol 49, Iss , Pp 101270- (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2352-9067 |
| DOI: |
10.1016/j.ijcha.2023.101270 |
| Popis: |
Background: Hepatitis C (HCV) infections have been shown to be associated a with higher risk of atherosclerotic cardiovascular disease (CVD). However, the use of antiviral therapy (AVT) and the risk of CVD has not been well established with limited literature. Objective: We sought to evaluate the association between AVT use post-HCV infection and cardiovascular outcomes. Methods: We performed a systematic literature search using PubMed, Embase, and Scopus for relevant articles from inception until 10th March 2023. Primary clinical outcomes were the incidence of any CVD. Secondary endpoints were all-cause of mortality, stroke, myocardial infarction, and peripheral artery disease. Results: A total of 394,452 patients were included in the analysis (111,076 in the AVT group and 283,376 patients in the NAVT group). The mean age of patients among AVT and NAVT groups was comparable (58.7 vs 58.18). The pooled analysis of primary outcomes showed that AVT was associated with a significantly reduced risk of any CVD (HR, 0.55(95%CI: 0.41–0.75), P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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