Evaluation of NPHS2 gene polymorphism (R229Q) in chronic kidney disease patients
| Autor: | Ahmed Mohamed rashid, Rania Elsayed sheir, Thoraya Mohamed Ahmed, Hanan Mohamed Farhan |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Egyptian Journal of Medical Research, Vol 2, Iss 2, Pp 20-30 (2021) |
| Druh dokumentu: | article |
| ISSN: | 2682-4396 2682-440X |
| DOI: | 10.21608/ejmr.2021.174556 |
| Popis: | The aim of this study was to evaluate the role of nephrotic syndrome 2 (NPHS2) gene polymorphism (R229Q) in chronic kidney disease which has unclear etiology. This study was conducted on 80 CKD patients compared with 40 age and sex matched normal volunteers acting as a control group. All of them underwent renal function tests and were assessed for the presence of NPHS2 gene polymorphism. We noticed that (R229Q) is a common variant in Egyptian population. Its concentration was (62.5%) in CKD patients and (55%) in control group. There was no significant difference with p-value > 0.05 between patients and control groups as regards to NPHS2 genotypes and alleles. |
| Databáze: | Directory of Open Access Journals |
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