Comparing chronic obstructive pulmonary disease and depressive disorder in terms of inflammation-related biomarkers

Autor: Elżbieta Małujło-Balcerska, Kasper Sipowicz, Tadeusz Pietras
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Archives of Medical Science, Vol 19, Iss 3, Pp 814-819 (2023)
Druh dokumentu: article
ISSN: 1734-1922
1896-9151
DOI: 10.5114/aoms/161803
Popis: Introduction Chronic obstructive pulmonary disease (COPD) is characterized by the presence of depressive symptoms. Material and methods Cytokine and deiodinase iodothyronines (DIOs) levels were evaluated in COPD patients and patients diagnosed with depressive disorder and control individuals. using enzyme-linked immunosorbent assays. Results Interleukin 1β (IL-1β), and tumor necrosis factor-a (TNF-a) levels were higher in COPD and depression patients than in control individuals. DIO2 were significantly lower in COPD and recurrent depressive disorder (rDD) patients than in controls. Conclusions Changes in the levels of IL-1β, TNF-a and DIO2 in COPD patients may explain the presence of depression in COPD patients.
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