Hyperglycemia in patients with combat injuries

Autor: Svetlana V. Topolyanskaya, Maria N. Kurzhos, Leonid I. Bubman, Yulia Yu. Vasilyeva, Maria V. Golimbekova, Ksenia D. Melnikova, Tatiana M. Kolontai, Medina Kh. Pilyarova, Alexander Yu. Molochnikov, Gayane Yu. Melik-Ogandjanyan, Karine A. Lytkina, Georgiy G. Melkonyan, Svetlana A. Rachina
Jazyk: English<br />Russian
Rok vydání: 2024
Předmět:
Zdroj: Клинический разбор в общей медицине, Vol 5, Iss 4, Pp 24-32 (2024)
Druh dokumentu: article
ISSN: 2713-2552
DOI: 10.47407/kr2024.5.4.00416
Popis: Aim. To investigate the prevalence and some aspects of the carbohydrate metabolism pathology in patients with combat limb injuries. Materials and methods. 210 patients who suffered from combat injuries of the lower and/or upper extremities from 4 to 58 days (mean 15.9±8.7 days) before admission to the hospital were enrolled in the study. All study participants were men. The mean age of the patients was 36.0±8.4 years (19–59 years). Fasting venous blood glucose concentrations were determined in all patients. Patients with hyperglycemia underwent a study of the glycemic profile and HbA1c. Stress-induced hyperglycemia, estimated mean glucose level over the past 3 months (ADAG), and glycemic gap were calculated. Insulin in fasting blood plasma was determined and the HOMA-IR insulin resistance index was calculated. Results. The incidence of hyperglycemia was 23.3%. In the general group of patients, the mean glucose concentration was 5.5±1.0 mmol/l (3.1–9.73 mmol/l). In the group of patients with hyperglycemia, the mean blood glucose level reached 6.7±0.9 mmol/l, in patients with normal glucose concentration – 5.1±0.5 mmol/l (p
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