| Autor: |
Ane Abad-motos, Jesús Troya, Eva Jiménez, Mario Fontán-Vela, Jorge Valencia, Ines Fernandez-Jimenez, Elena Alba Álvaro-Alonso, Elsa Izquierdo-García, Andrea Lazaro Cebas, Elisa Gallego Ruiz-Elvira, Ana Josefa Tebar-Martinez, Belén Garcia-Marina, Gabriela Peña-Lillo, Laura Macaya, Pablo Ryan, Mario Pérez-Butragueño, Blanca Herrero Mendoza, Natividad Plazas Andreu, Liliana Vázquez Bol, Sandra María Gadin López, Álvaro Martínez Alcalá, Sonia Pérez Gonzalez, Amalia Martínez de la Gándara, Alejandro Zuazua Gonzalez, Javier Montoya Adarraga, Miguel Ángel Lara Álvarez, Enrique Calvo Aranda, Rosa M Lorente Ramos, María Alcantud, Roberto Alcázar Arroyo, Verónica Suberviola Sánchez-Caballero, Ariela Candelario Cáceres, Juan Churruca Sarasqueta, Juan Torres Macho, Ismael Escobar Rodríguez, Raquel Ruíz Páez, Alberto Esquivel López, Pablo de la Cueva Dobao, Natalia Blanca López, José García Hinojosa, Cristina Sevillano Collantes, Alfonso Camacho Aroca, Tamar Talaván Zañón, María Ángeles Sánchez Úriz, Carlos Bibiano Guillén, Miguel Ángel López Arenas, Margarita Gimeno Arández, Francisco Javier Quintero Gutiérrez del Álamo |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
BMJ Open, Vol 10, Iss 11 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2044-6055 |
| DOI: |
10.1136/bmjopen-2020-042398 |
| Popis: |
Objectives To describe demographic, clinical, radiological and laboratory characteristics, as well as outcomes, of patients admitted for COVID-19 in a secondary hospital.Design and setting Retrospective case series of sequentially hospitalised patients with confirmed SARS-CoV-2, at Infanta Leonor University Hospital (ILUH) in Madrid, Spain.Participants All patients attended at ILUH testing positive to reverse transcriptase-PCR on nasopharyngeal swabs and diagnosed with COVID-19 between 1 March 2020 and 28 May 2020.Results A total of 1549 COVID-19 cases were included (median age 69 years (IQR 55.0–81.0), 57.5% men). 78.2% had at least one underlying comorbidity, the most frequent was hypertension (55.8%). Most frequent symptoms at presentation were fever (75.3%), cough (65.7%) and dyspnoea (58.1%). 81 (5.8%) patients were admitted to the intensive care unit (ICU) (median age 62 years (IQR 51–71); 74.1% men; median length of stay 9 days (IQR 5–19)) 82.7% of them needed invasive ventilation support. 1393 patients had an outcome at the end of the study period (case fatality ratio: 21.2% (296/1393)). The independent factors associated with fatality (OR; 95% CI): age (1.07; 1.06 to 1.09), male sex (2.86; 1.85 to 4.50), neurological disease (1.93; 1.19 to 3.13), chronic kidney disease (2.83; 1.40 to 5.71) and neoplasia (4.29; 2.40 to 7.67). The percentage of hospital beds occupied with COVID-19 almost doubled (702/361), with the number of patients in ICU quadrupling its capacity (32/8). Median length of stay was 9 days (IQR 6–14).Conclusions This study provides clinical characteristics, complications and outcomes of patients with COVID-19 admitted to a European secondary hospital. Fatal outcomes were similar to those reported by hospitals with a higher level of complexity. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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