Characteristic CT features of pheochromocytomas - probability model calculation tool based on a multicentric study

Autor: Filip Ctvrtlik, Zbynek Tudos, Paulina Szasz, Zuzana Sedlackova, Igor Hartmann, Jan Schovanek, Zdenek Frysak, Iva Macova, Tomas Zelinka, Milan Hora, Eva Kocova, Jaroslav Pacovsky, Michal Krsek, Viera Lehotska, Emilia Mojtova, Josef Molnar, Vladimir Vanek, Karel Pacak, Jan Baxa
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Biomedical Papers, Vol 163, Iss 3, Pp 212-219 (2019)
Druh dokumentu: article
ISSN: 1213-8118
1804-7521
DOI: 10.5507/bp.2019.047
Popis: Objectives: The aim of the study was to evaluate the CT features of adrenal tumors in an effort to identify features specific to pheochromocytomas and second, to define a feasible probability calculation model. Methods: This multicentric retrospective study included patients from the period 2003 to 2017 with an appropriate CT examination and a histological diagnosis of an adrenal adenoma, pheochromocytoma, adrenocortical carcinoma, or metastasis. In total, 346 patients were suitable for the CT image analysis, which included evaluation of the largest diameter, the shape of the lesion, the presence of central necrosis and its margins, and the presence of an enhancing peripheral rim ("ring sign"). Results: Pheochromocytomas have a significantly more spherical shape (P
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