Genome-Wide Association Study of Metabolic Syndrome in Koreans

Autor: Seok Won Jeong, Myungguen Chung, Soo-Jung Park, Seong Beom Cho, Kyung-Won Hong
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Genomics & Informatics, Vol 12, Iss 4, Pp 187-194 (2014)
Druh dokumentu: article
ISSN: 1598-866X
2234-0742
DOI: 10.5808/GI.2014.12.4.187
Popis: Metabolic syndrome (METS) is a disorder of energy utilization and storage and increases the risk of developing cardiovascular disease and diabetes. To identify the genetic risk factors of METS, we carried out a genome-wide association study (GWAS) for 2,657 cases and 5,917 controls in Korean populations. As a result, we could identify 2 single nucleotide polymorphisms (SNPs) with genome-wide significance level p-values (
Databáze: Directory of Open Access Journals