Glucocorticoid Withdrawal Symptoms and Quality of Life in Patients with Systemic Lupus Erythematosus

Autor:	Matee Karoonkatima, Pongthorn Narongroeknawin, Sumapa Chaiamnuay, Paijit Asavatanabodee, Rattapol Pakchotanon
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	Diseases of the musculoskeletal system RC925-935
Zdroj:	International Journal of Rheumatology, Vol 2023 (2023)
Druh dokumentu:	article
ISSN:	1687-9279
DOI:	10.1155/2023/5750791
Popis:	Background/Objective. Chronic glucocorticoid (GCS) therapy is associated with increased risk of organ damage in systemic lupus erythematosus (SLE). However, discontinuation of low-dose GCS might cause withdrawal symptoms. This study is aimed at identifying GCS withdrawal symptoms and health-related quality of life (HRQoL) among SLE patients. Methods. SLE patients whose prednisolone had been previously withdrawn or taken 9), but not statistically significant (40% vs. 20.6%, p=0.34). PROs were comparable between groups. Independent factors associated with SLEQoL were FACIT (adjusted β 1.31, 95% CI 0.76, 1.86, p
Databáze:	Directory of Open Access Journals
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