Comparison of the intima‐media thickness of the common carotid artery in patients with rheumatoid arthritis: A single‐center cross‐sectional case‐control study, and a brief review of the literature

Autor: Farnood Rajabzadeh, Iman Akhlaghipour, Sahar Sadat Moosavi, Arya Nasimi Shad, Atefeh Babazadeh Baghan, Zhaleh Shariati‐Sarabi, Asma Payandeh, Ehsan Hassan Nejad
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Health Science Reports, Vol 6, Iss 11, Pp n/a-n/a (2023)
Druh dokumentu: article
ISSN: 2398-8835
DOI: 10.1002/hsr2.1718
Popis: Abstract Background and Aim Rheumatoid arthritis (RA) is an autoimmune chronic inflammatory disease affecting 0.5%−1% of adults worldwide. The carotid intima‐media thickness (CIMT) is a simple, reliable, noninvasive marker for subclinical atherosclerosis. The aim of this study was to compare the intima‐media thickness of the common carotid artery in patients with RA with that of healthy patients. Methods In this case‐control study, subjects were recruited from the patients who presented to a private rheumatology clinic. RA was documented by a rheumatologist. All subjects underwent an ultrasound examination of the carotid artery to assess CIMT. Subjects with RA filled out the disease activity score (DAS28) questionnaire. Results Sixty‐two subjects (31 subjects with RA and 31 healthy subjects) took part in the study. The mean age of the subjects in the RA and the control groups was 42.39 ± 12.98 and 44.48 ± 13.56 years, respectively. Values of CIMT were significantly greater in RA subjects compared with their healthy counterparts (p 40 years). A comparison of CIMT in the mentioned subgroups revealed a remarkable difference in CIMT values between those of the RA patients and those of their control counterparts in both age groups (p = 0.002 and p
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