Attention should be paid to false-positive results due to heterophilic antibodies interfering with Abbott high-sensitivity cardiac troponin I assay
Autor: | Liu Weiping, Long Xia, Chen Lulu, Yang Kailan |
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Jazyk: | angličtina |
Rok vydání: | 2024 |
Předmět: | |
Zdroj: | Journal of Laboratory Medicine, Vol 48, Iss 3, Pp 137-140 (2024) |
Druh dokumentu: | article |
ISSN: | 2567-9430 2567-9449 |
DOI: | 10.1515/labmed-2023-0131 |
Popis: | In recent years, chemiluminescent microparticle immunoassay (CMIA) has been widely used for determination of high-sensitivity troponin I (hs-cTnI). However, a CMIA analysis is usually affected by the presence of some endogenous or exogenous substances. This case-report aims to unveil the essence of the reoccurrence of false-positive results due to heterophilic antibodies interference with Abbott high-sensitivity cardiac troponin I assay, although the assay method applied a chimeric antibody. |
Databáze: | Directory of Open Access Journals |
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