Attention should be paid to false-positive results due to heterophilic antibodies interfering with Abbott high-sensitivity cardiac troponin I assay

Autor: Liu Weiping, Long Xia, Chen Lulu, Yang Kailan
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of Laboratory Medicine, Vol 48, Iss 3, Pp 137-140 (2024)
Druh dokumentu: article
ISSN: 2567-9430
2567-9449
DOI: 10.1515/labmed-2023-0131
Popis: In recent years, chemiluminescent microparticle immunoassay (CMIA) has been widely used for determination of high-sensitivity troponin I (hs-cTnI). However, a CMIA analysis is usually affected by the presence of some endogenous or exogenous substances. This case-report aims to unveil the essence of the reoccurrence of false-positive results due to heterophilic antibodies interference with Abbott high-sensitivity cardiac troponin I assay, although the assay method applied a chimeric antibody.
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