Spontaneous pneumococcal peritonitis diagnosed by qPCR

Autor: Daniel Jarovsky, Thais Grodzicki Ambrus, Mariana Galvão Gurgel, Marcelo Jenné Mimica, Mariana Volpe Arnoni, Flávia Jacqueline Almeida, Marco Aurélio Palazzi Sáfadi, Eitan Naaman Berezin
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: IDCases, Vol 15, Iss , Pp - (2019)
Druh dokumentu: article
ISSN: 2214-2509
DOI: 10.1016/j.idcr.2019.e00489
Popis: Spontaneous bacterial peritonitis is an uncommon manifestation of invasive pneumococcal disease and frequently occurs when an underlying hepatic disease is present. Bacterial identification through culture can be particularly challenging in patients with prior or concurrent antimicrobial use. DNA amplification detects very few copies of target DNA under ideal conditions in CSF or pleural effusion and, therefore, can be useful in selected infections. A culture-negative spontaneous pneumococcal peritonitis without preexisting peritoneal disease diagnosed by qPCR is herein described. Keywords: Streptococcus pneumoniae, Invasive pneumococcal disease, Spontaneous peritonitis, Real-time PCR, lytA primer
Databáze: Directory of Open Access Journals