Autor: |
Soha M. Hamdy, Yomna A. Othman, Omayma O. Abdelaleem, Rehab G. Abd El-Hamid, Doaa Y. Ali |
Jazyk: |
angličtina |
Rok vydání: |
2024 |
Předmět: |
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Zdroj: |
Egyptian Pediatric Association Gazette, Vol 72, Iss 1, Pp 1-9 (2024) |
Druh dokumentu: |
article |
ISSN: |
2090-9942 |
DOI: |
10.1186/s43054-024-00260-8 |
Popis: |
Abstract Background Neonatal sepsis is one of the life-threatening diseases. MicroRNAs are non-coding RNAs that play vital roles in various diseases. Methods This study included 50 neonates with sepsis and 60 healthy controls. RNA extraction and assessment of mir-182-5p and miR-590-3p using real-time PCR were done. Results Significant downregulation of mir-182-5p and miR-590-3p in neonates with sepsis compared with healthy neonates was observed. Positive correlations were confirmed between the expression levels of miR-182-5p and birth weight (R = 0.355, P = 0.012), RDW (R = 0.476, p = |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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