Patients exposed to vancomycin-resistant enterococci during in-hospital outbreaks in a low endemic setting: a proposal for risk-based screening

Autor: Andrea C. Büchler, Silvio Ragozzino, Melanie Wicki, Violeta Spaniol, Sammy Jäger, Helena M. B. Seth-Smith, Daniel Goldenberger, Vladimira Hinic, Adrian Egli, Reno Frei, Andreas F. Widmer
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Antimicrobial Resistance and Infection Control, Vol 11, Iss 1, Pp 1-7 (2022)
Druh dokumentu: article
ISSN: 2047-2994
DOI: 10.1186/s13756-022-01089-9
Popis: Abstract Background The optimal extent of screening of contact patients (CoPat) after exposure to patients infected or colonized with vancomycin-resistant enterococci (VRE) remains controversial. Methods We retrospectively developed a new risk stratification for screening patients exposed to VRE, based on data from three outbreaks—two with Enterococcus faecium vanB and one with Enterococcus faecium vanA involving 1096 CoPat—in a low endemic setting. We classified them into four risk groups: three on environmental exposure, one by healthcare exposure: high (sharing the same room/bathroom with a VRE-colonized patient), medium (hospitalization in the same room after a VRE-colonized patient’s discharge until terminal disinfection including ultraviolet C (UVc)-disinfection), low (hospitalized in the same room within three weeks before the VRE-colonized patient), and “staff” (screening of patients having the same medical care team). Results VRE-transmission occurred in 7.9% in the high-risk group compared to 0.6% and 0% in the medium and low risk groups. There was a significant trend to higher rates of transmission by risk level of exposure (p
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