Validation of KDRI/KDPI for the selection of expanded criteria kidney donors

Autor: Raimundo M. García del Moral Martín, Juan Antonio Retamero Díaz, Mercedes Cava Molina, Belen M. Cobacho Tornel, Juan Bravo Soto, Antonio Osuna Ortega, Francisco O’Valle Ravassa, Raimundo García del Moral Garrido
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Nefrología (English Edition), Vol 38, Iss 3, Pp 297-303 (2018)
Druh dokumentu: article
ISSN: 2013-2514
DOI: 10.1016/j.nefroe.2017.12.003
Popis: Introduction: KDRI/KDPI are tools use in kidney donor evaluation. It has been proposed as a substitute of, or complementary to preimplantation renal biopsy. These scores have not been validated in Spain. Objective: (1) To investigate the concordance between KDPI and histological scores (preimplantation renal biopsy) and (2) to assess the relationship between KDRI, KDPI and histological score on graft survival in the expanded criteria donors group. Methodology: Retrospective cohort study from 1 January 1998 to 31 December 2010. Results: During the study 120 donors were recruited, that resulted in 220 preimplantation renal biopsies. 144 (65%) grafts were considered suitable for kidney transplantation. 76 (34.5%) were discarded. Median follow up has been 6.4 years (sd 3.9). Median age 63.1 years (sd 8.2), males (145; 65.9%), non-diabetic (191; 86.8%) and without another cardiovascular risk factors (173; 78.6%). 153 (69.5%) donors died of cerebrovascular disease. There were significant differences in KDRI/KDPI score in both groups 1.56/89 (sd 0.22) vs 1.66/93 (sd 0.15), p
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