Predictors of outcome in refractory generalized convulsive status epilepticus

Autor: Dilli Ram Kafle, Appu Jha Avinash, Aashish Shrestha
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Epilepsia Open, Vol 5, Iss 2, Pp 248-254 (2020)
Druh dokumentu: article
ISSN: 2470-9239
DOI: 10.1002/epi4.12394
Popis: Abstract Objective Refractory status epilepticus is a serious condition in which seizure continues despite use of two antiepileptic medications. Retrospective studies have shown that 29%‐43% of SE patients progress into RSE despite treatment. Mortality following RSE is high. We aimed to evaluate the predictors of outcome in patients with RSE at a tertiary care center. Methods Sixty‐eight consecutive patients with RSE who presented to our hospital between February 2018 and January 2020 were evaluated for outcome. Result In our study 28(41.2%), patients who failed to respond to first‐ and second‐line antiepileptic drug responded to the third‐line antiepileptic drug thus avoiding mechanical ventilation and intravenous anesthesia. Low GCS at admission (P
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