| Autor: |
Felix Troger, Ivan Lechner, Martin Reindl, Christina Tiller, Magdalena Holzknecht, Mathias Pamminger, Christian Kremser, Johannes Schwaiger, Sebastian J. Reinstadler, Axel Bauer, Bernhard Metzler, Agnes Mayr, Gert Klug |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Journal of Cardiovascular Magnetic Resonance, Vol 24, Iss 1, Pp 1-13 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
1532-429X |
| DOI: |
10.1186/s12968-021-00838-w |
| Popis: |
Abstract Background Transthoracic echocardiography (TTE) is the diagnostic routine standard for assessing aortic stenosis (AS). However, its inaccuracies in determining stroke volume (SV) and aortic valve area (AVA) call for a more precise and dependable method. Phase-contrast cardiovascular magnetic resonance imaging (PC-CMR) is a promising tool to push these boundaries. Thus, the aim of this study was to validate a novel approach based on PC-CMR against the gold-standard of invasive determination of AVA in AS compared to TTE. Methods A total of 50 patients with moderate or severe AS underwent TTE, cardiac catheterization and CMR. AVA via PC-CMR was determined by plotting momentary flow across the valve against flow-velocity. SV by CMR was measured directly via PC-CMR and volumetrically using cine-images. Invasive SV and AVA were determined via Fick-principle and Gorlin-formula, respectively. TTE yielded SV and AVA using continuity equation. Gradients were calculated via the modified Bernoulli-equation. Results SV by PC-CMR (85 ± 31 ml) correlated strongly (r: 0.73, p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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