LABORATORY AND GENETIC PREDICTION OF THE RISK OF ATRIAL FIBRILLATION IN PATIENTS WITH CORONARY HEART DISEASE

Autor: D. I. PANCHENKO, A. S. ADAMCHIK
Jazyk: ruština
Rok vydání: 2017
Předmět:
Zdroj: Кубанский научный медицинский вестник, Vol 1, Iss 1, Pp 106-109 (2017)
Druh dokumentu: article
ISSN: 1608-6228
2541-9544
DOI: 10.25207/1608-6228-2017-1-106-109
Popis: The paper studied the frequency of polymorphisms of hemostasis in patients with coronary heart disease, living in the Krasnodar region. Of the 13 patients with atrial fibrillation documented confirmed, 11 patients revealed mutations of genes of the hemostatic system (84.61 %), while 10 patients out of 11 had a mutation MTRR mutation (90.9 %), and met mutations in polygenic 10 cases (90.9 %). It is shown that the most common mutation MTRR gene, PAI, VII factor and beta fibrin often cause arrhythmias in patients enhance remodeling of the left ventricle, especially in polygenic mutations.
Databáze: Directory of Open Access Journals