Inhibition of cysteine peptidase activity in ascitic fluid in pancreatic cancer patients.
Autor: | Adam Skalski, Zgmunt Grzebieniak, Abdo Katib, Wojciech Kielan, Anil Kumar Agrawal, Tomasz Grzebieniak, Lukasz Duda-Barcik, Anna Janocha, Maciej Siewiński |
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Jazyk: | angličtina |
Rok vydání: | 2011 |
Předmět: | |
Zdroj: | Folia Histochemica et Cytobiologica, Vol 48, Iss 4, Pp 513-517 (2011) |
Druh dokumentu: | article |
ISSN: | 0239-8508 1897-5631 |
DOI: | 10.5603/4172 |
Popis: | The work's objective is to answer the question whether there is any possibility of activity inhibition of cysteine peptidases inhibitors playing an important role in key processes accompanying cancer formation, including pancreas. There is a justified speculation that specific inhibitors of these enzymes may inhibit development of cancer processes by inhibiting their activity. In vitro studies confirmed that these enzymes in ascitic fluid were inhibited with egg whites inhibitors even to 90% of their original activity. |
Databáze: | Directory of Open Access Journals |
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