| Autor: |
Shifan Zhu, Jiayu Zhang, Langping Gao, Qing Ye, Jianhua Mao |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
|
| Zdroj: |
Kidney Diseases, Pp 1-14 (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2296-9357 |
| DOI: |
10.1159/000540511 |
| Popis: |
Background: Nephrotic syndrome is a special type of chronic kidney disease, the specific pathogenesis of which remains unclear. An increasing number of studies have suggested that B cells play an important role in the pathogenesis of nephrotic syndrome. Summary: Idiopathic nephrotic syndrome is a common kidney disease in children. While previously believed to be primarily caused by T-cell disorders, recent research has shifted its focus to B cells. Studies have shown that B cells play a significant role in the pathogenesis of NS, potentially even more so than T cells. This article provides a comprehensive review of the involvement of B cells in the development of idiopathic nephrotic syndrome. Key Messages: B cells are involved in the pathogenesis of nephrotic syndrome by producing autoantibodies and various cytokines. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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