VINEdb: a data warehouse for integration and interactive exploration of life science data

Autor: Hariharaputran Sridhar, Töpel Thoralf, Brockschmidt Björn, Hofestädt Ralf
Jazyk: angličtina
Rok vydání: 2007
Předmět:
Zdroj: Journal of Integrative Bioinformatics, Vol 4, Iss 3, Pp 41-51 (2007)
Druh dokumentu: article
ISSN: 1613-4516
DOI: 10.1515/jib-2007-63
Popis: Control of cell proliferation, differentiation, activation and cell removal is crucial for the development and existence of multi-cellular organisms. Apoptosis, or programmed cell death, is a major control mechanism by which cells die and is also important in controlling cell number and proliferation as part of normal development. Molecular networks that regulate these processes are critical targets for drug development, gene therapy, and metabolic engineering. The molecular interactions involved in this and other processes are analyzed and annotated by experts and stored as data in different databases. The key task is to integrate, manage and visualize these data available from different sources and present them in a user-comprehensible manner.
Databáze: Directory of Open Access Journals